Super-resolution visualization of distinct stalled and broken replication fork structures

Endogenous genotoxic stress occurs in healthy cells due to competition between DNA replication machinery, and transcription and topographic relaxation processes. This causes replication fork stalling and regression, which can further collapse to form single-ended double strand breaks (seDSBs). Super...

Descripción completa

Detalles Bibliográficos
Autores principales: Whelan, Donna R., Lee, Wei Ting C., Marks, Frances, Kong, Yu Tina, Yin, Yandong, Rothenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793303/
https://www.ncbi.nlm.nih.gov/pubmed/33370257
http://dx.doi.org/10.1371/journal.pgen.1009256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793303/
https://www.ncbi.nlm.nih.gov/pubmed/33370257
http://dx.doi.org/10.1371/journal.pgen.1009256

Ejemplares similares