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High Risk α-HPV E6 Impairs Translesion Synthesis by Blocking POLη Induction
SIMPLE SUMMARY: Cervical cancers (CaCx) are caused by the expression of human papillomavirus oncogenes (HPV E6 and E7). Here, in vitro assays, computational approaches and immunohistochemical analysis of cervical biopsies show that HPV oncogenes impair translesion synthesis (TLS). This limits the pa...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793514/ https://www.ncbi.nlm.nih.gov/pubmed/33374731 http://dx.doi.org/10.3390/cancers13010028 |