Photoinduced Endosomal Escape Mechanism: A View from Photochemical Internalization Mediated by CPP-Photosensitizer Conjugates

Endosomal escape in cell-penetrating peptide (CPP)-based drug/macromolecule delivery systems is frequently insufficient. The CPP-fused molecules tend to remain trapped inside endosomes and end up being degraded rather than delivered into the cytosol. One of the methods for endosomal escape of CPP-fu...

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Detalles Bibliográficos
Autores principales: Soe, Tet Htut, Watanabe, Kazunori, Ohtsuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793540/
https://www.ncbi.nlm.nih.gov/pubmed/33374732
http://dx.doi.org/10.3390/molecules26010036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793540/
https://www.ncbi.nlm.nih.gov/pubmed/33374732
http://dx.doi.org/10.3390/molecules26010036

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