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Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence

Telomeres have the ability to adopt a lariat conformation and hence, engage in long and short distance intra-chromosome interactions. Budding yeast telomeres were proposed to fold back into subtelomeric regions, but a robust assay to quantitatively characterize this structure has been lacking. There...

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Detalles Bibliográficos
Autores principales: Wagner, Tina, Pérez-Martínez, Lara, Schellhaas, René, Barrientos-Moreno, Marta, Öztürk, Merve, Prado, Félix, Butter, Falk, Luke, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793543/
https://www.ncbi.nlm.nih.gov/pubmed/33370275
http://dx.doi.org/10.1371/journal.pgen.1008603