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Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence
Telomeres have the ability to adopt a lariat conformation and hence, engage in long and short distance intra-chromosome interactions. Budding yeast telomeres were proposed to fold back into subtelomeric regions, but a robust assay to quantitatively characterize this structure has been lacking. There...
Autores principales: | Wagner, Tina, Pérez-Martínez, Lara, Schellhaas, René, Barrientos-Moreno, Marta, Öztürk, Merve, Prado, Félix, Butter, Falk, Luke, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793543/ https://www.ncbi.nlm.nih.gov/pubmed/33370275 http://dx.doi.org/10.1371/journal.pgen.1008603 |
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