The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments

Cell migration in confining microenvironments is limited by the ability of the stiff nucleus to deform through pores when migration paths are preexisting and elastic, but how cells generate these paths remains unclear. Here, we reveal a mechanism by which the nucleus mechanically generates migration...

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Detalles Bibliográficos
Autores principales: Lee, Hong-pyo, Alisafaei, Farid, Adebawale, Kolade, Chang, Julie, Shenoy, Vivek B., Chaudhuri, Ovijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793582/
https://www.ncbi.nlm.nih.gov/pubmed/33523987
http://dx.doi.org/10.1126/sciadv.abd4058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793582/
https://www.ncbi.nlm.nih.gov/pubmed/33523987
http://dx.doi.org/10.1126/sciadv.abd4058

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