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The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments
Cell migration in confining microenvironments is limited by the ability of the stiff nucleus to deform through pores when migration paths are preexisting and elastic, but how cells generate these paths remains unclear. Here, we reveal a mechanism by which the nucleus mechanically generates migration...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793582/ https://www.ncbi.nlm.nih.gov/pubmed/33523987 http://dx.doi.org/10.1126/sciadv.abd4058 |