ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism

Inter-α-inhibitor heavy chain 4 (ITIH4) is a poorly characterized plasma protein that is proteolytically processed in multiple pathological conditions. However, no biological function of ITIH4 has been identified. Here, we show that ITIH4 is cleaved by several human proteases within a protease-susce...

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Detalles Bibliográficos
Autores principales: Pihl, Rasmus, Jensen, Rasmus K., Poulsen, Emil C., Jensen, Lisbeth, Hansen, Annette G., Thøgersen, Ida B., Dobó, József, Gál, Péter, Andersen, Gregers R., Enghild, Jan J., Thiel, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793589/
https://www.ncbi.nlm.nih.gov/pubmed/33523981
http://dx.doi.org/10.1126/sciadv.aba7381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793589/
https://www.ncbi.nlm.nih.gov/pubmed/33523981
http://dx.doi.org/10.1126/sciadv.aba7381

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