A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes

Hundreds of human genes are associated with neurological diseases, but translation into tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to investigate genetic contributions to neurological diseases. However, current CRISPR-Cas9 methods are difficult to apply to l...

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Detalles Bibliográficos
Autores principales: Kroll, François, Powell, Gareth T, Ghosh, Marcus, Gestri, Gaia, Antinucci, Paride, Hearn, Timothy J, Tunbak, Hande, Lim, Sumi, Dennis, Harvey W, Fernandez, Joseph M, Whitmore, David, Dreosti, Elena, Wilson, Stephen W, Hoffman, Ellen J, Rihel, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793621/
https://www.ncbi.nlm.nih.gov/pubmed/33416493
http://dx.doi.org/10.7554/eLife.59683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793621/
https://www.ncbi.nlm.nih.gov/pubmed/33416493
http://dx.doi.org/10.7554/eLife.59683

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