Cargando…
A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
Hundreds of human genes are associated with neurological diseases, but translation into tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to investigate genetic contributions to neurological diseases. However, current CRISPR-Cas9 methods are difficult to apply to l...
Autores principales: | Kroll, François, Powell, Gareth T, Ghosh, Marcus, Gestri, Gaia, Antinucci, Paride, Hearn, Timothy J, Tunbak, Hande, Lim, Sumi, Dennis, Harvey W, Fernandez, Joseph M, Whitmore, David, Dreosti, Elena, Wilson, Stephen W, Hoffman, Ellen J, Rihel, Jason |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793621/ https://www.ncbi.nlm.nih.gov/pubmed/33416493 http://dx.doi.org/10.7554/eLife.59683 |
Ejemplares similares
-
Whole-brain mapping of socially isolated zebrafish reveals that lonely fish are not loners
por: Tunbak, Hande, et al.
Publicado: (2020) -
Pretectal neurons control hunting behaviour
por: Antinucci, Paride, et al.
Publicado: (2019) -
A crystal-clear zebrafish for in vivo imaging
por: Antinucci, Paride, et al.
Publicado: (2016) -
Orientation-Selective Retinal Circuits in Vertebrates
por: Antinucci, Paride, et al.
Publicado: (2018) -
A standard knockout procedure alters expression of adjacent loci at the translational level
por: Egorov, Artyom A, et al.
Publicado: (2021)