MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to drive pro-tumorigenic gene expression programs, pr...

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Detalles Bibliográficos
Autores principales: Popay, Tessa M, Wang, Jing, Adams, Clare M, Howard, Gregory Caleb, Codreanu, Simona G, Sherrod, Stacy D, McLean, John A, Thomas, Lance R, Lorey, Shelly L, Machida, Yuichi J, Weissmiller, April M, Eischen, Christine M, Liu, Qi, Tansey, William P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793627/
https://www.ncbi.nlm.nih.gov/pubmed/33416496
http://dx.doi.org/10.7554/eLife.60191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793627/
https://www.ncbi.nlm.nih.gov/pubmed/33416496
http://dx.doi.org/10.7554/eLife.60191

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