Reciprocal Induction of MDM2 and MYCN in Neural and Neuroendocrine Cancers

MYC family oncoproteins MYC, MYCN, and MYCL are deregulated in diverse cancers and via diverse mechanisms. Recent studies established a novel form of MYCN regulation in MYCN-overexpressing retinoblastoma and neuroblastoma cells in which the MDM2 oncoprotein promotes MYCN translation and MYCN-depende...

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Detalles Bibliográficos
Autores principales: Tran, Hung N., Singh, Hardeep P., Guo, Wenxuan, Cambier, Linda, Riggan, Luke, Shackleford, Gregory M., Thornton, Matthew E., Grubbs, Brendan H., Erdreich-Epstein, Anat, Qi, Dong-Lai, Cobrinik, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793692/
https://www.ncbi.nlm.nih.gov/pubmed/33425720
http://dx.doi.org/10.3389/fonc.2020.563156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793692/
https://www.ncbi.nlm.nih.gov/pubmed/33425720
http://dx.doi.org/10.3389/fonc.2020.563156

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