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Endothelial Cells Promote Docetaxel Resistance of Prostate Cancer Cells by Inducing ERG Expression and Activating Akt/mTOR Signaling Pathway

Docetaxel is a first-line chemotherapy for the treatment of patients with castration-resistant prostate cancer (CRPC). Despite the good initial response of docetaxel, drug resistance will inevitably occur. Mechanisms underlying docetaxel resistance are not well elaborated. Endothelial cells (ECs) ha...

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Detalles Bibliográficos
Autores principales: Zhou, Wenhao, Su, Yiming, Zhang, Yu, Han, Bangmin, Liu, Haitao, Wang, Xiaohai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793734/
https://www.ncbi.nlm.nih.gov/pubmed/33425737
http://dx.doi.org/10.3389/fonc.2020.584505