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Distinct Molecular Mechanisms Underlying Potassium Efflux for NLRP3 Inflammasome Activation

The NLRP3 inflammasome is a core component of innate immunity, and dysregulation of NLRP3 inflammasome involves developing autoimmune, metabolic, and neurodegenerative diseases. Potassium efflux has been reported to be essential for NLRP3 inflammasome activation by structurally diverse pathogen-asso...

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Detalles Bibliográficos
Autores principales: Xu, Ziwei, Chen, Zi-mo, Wu, Xiaoyan, Zhang, Linjie, Cao, Ying, Zhou, Pingzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793832/
https://www.ncbi.nlm.nih.gov/pubmed/33424864
http://dx.doi.org/10.3389/fimmu.2020.609441