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Distinct Molecular Mechanisms Underlying Potassium Efflux for NLRP3 Inflammasome Activation
The NLRP3 inflammasome is a core component of innate immunity, and dysregulation of NLRP3 inflammasome involves developing autoimmune, metabolic, and neurodegenerative diseases. Potassium efflux has been reported to be essential for NLRP3 inflammasome activation by structurally diverse pathogen-asso...
Autores principales: | Xu, Ziwei, Chen, Zi-mo, Wu, Xiaoyan, Zhang, Linjie, Cao, Ying, Zhou, Pingzheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793832/ https://www.ncbi.nlm.nih.gov/pubmed/33424864 http://dx.doi.org/10.3389/fimmu.2020.609441 |
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