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Sevoflurane Exposure Induces Neuronal Cell Parthanatos Initiated by DNA Damage in the Developing Brain via an Increase of Intracellular Reactive Oxygen Species

The safety of volatile anesthetics in infants and young children has been drawing increasing concern due to its potential neurotoxicity in the developing brain. Neuronal death is considered a major factor associated with developmental neurotoxicity after exposure to volatile anesthetics sevoflurane,...

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Detalles Bibliográficos
Autores principales: Piao, Meihua, Wang, Yingying, Liu, Nan, Wang, Xuedong, Chen, Rui, Qin, Jing, Ge, Pengfei, Feng, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793874/
https://www.ncbi.nlm.nih.gov/pubmed/33424554
http://dx.doi.org/10.3389/fncel.2020.583782