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Stable Expression of a Hepatitis E Virus (HEV) RNA Replicon in Two Mammalian Cell Lines to Assess Mechanism of Innate Immunity and Antiviral Response

Hepatitis E virus (HEV) is one of the major etiological agents responsible for acute hepatitis. Hepatitis E virus does not replicate efficiently in mammalian cell cultures, thus a useful model that mimics persistent HEV replication is needed to dissect the molecular mechanism of pathogenesis. Here w...

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Detalles Bibliográficos
Autores principales: Xu, Ling-Dong, Zhang, Fei, Peng, Lei, Luo, Wen-Ting, Chen, Chu, Xu, Pinglong, Huang, Yao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793998/
https://www.ncbi.nlm.nih.gov/pubmed/33424806
http://dx.doi.org/10.3389/fmicb.2020.603699