CRISPR/Cas9 mediated knock-out of VPREB1 gene induces a cytotoxic effect in myeloma cells

BACKGROUND: Multiple Myeloma (MM) is a heterogeneous, hematological neoplasm that accounts 2% of all cancers. Although, autologous stem cell transplantation and chemotherapy are currently the most effective therapy, it carries a notable hazards, in addition for being non curative. Recently, the Clus...

Descripción completa

Detalles Bibliográficos
Autores principales: Khaled, Mai, Moustafa, Amr S., El-Khazragy, Nashwa, Ahmed, Maha Imam, Abd Elkhalek, Marwa Ali, El_Salahy, Eman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794028/
https://www.ncbi.nlm.nih.gov/pubmed/33418558
http://dx.doi.org/10.1371/journal.pone.0245349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794028/
https://www.ncbi.nlm.nih.gov/pubmed/33418558
http://dx.doi.org/10.1371/journal.pone.0245349

Ejemplares similares