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CRISPR/Cas9 mediated knock-out of VPREB1 gene induces a cytotoxic effect in myeloma cells

BACKGROUND: Multiple Myeloma (MM) is a heterogeneous, hematological neoplasm that accounts 2% of all cancers. Although, autologous stem cell transplantation and chemotherapy are currently the most effective therapy, it carries a notable hazards, in addition for being non curative. Recently, the Clus...

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Detalles Bibliográficos
Autores principales:	Khaled, Mai, Moustafa, Amr S., El-Khazragy, Nashwa, Ahmed, Maha Imam, Abd Elkhalek, Marwa Ali, El_Salahy, Eman M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794028/ https://www.ncbi.nlm.nih.gov/pubmed/33418558 http://dx.doi.org/10.1371/journal.pone.0245349

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