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Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity

Human cytomegalovirus (HCMV) is the primary viral cause of congenital birth defects and causes significant morbidity and mortality in immune-suppressed transplant recipients. Despite considerable efforts in vaccine development, HCMV infection still represents an unmet clinical need. In recent phase...

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Detalles Bibliográficos
Autores principales: Perotti, Michela, Marcandalli, Jessica, Demurtas, Davide, Sallusto, Federica, Perez, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794029/
https://www.ncbi.nlm.nih.gov/pubmed/33370407
http://dx.doi.org/10.1371/journal.ppat.1009169