Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides

Microbial natural products constitute a wide variety of chemical compounds, many which can have antibiotic, antiviral, or anticancer properties that make them interesting for clinical purposes. Natural product classes include polyketides (PKs), nonribosomal peptides (NRPs), and ribosomally synthesiz...

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Detalles Bibliográficos
Autores principales: Kloosterman, Alexander M., Cimermancic, Peter, Elsayed, Somayah S., Du, Chao, Hadjithomas, Michalis, Donia, Mohamed S., Fischbach, Michael A., van Wezel, Gilles P., Medema, Marnix H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794033/
https://www.ncbi.nlm.nih.gov/pubmed/33351797
http://dx.doi.org/10.1371/journal.pbio.3001026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794033/
https://www.ncbi.nlm.nih.gov/pubmed/33351797
http://dx.doi.org/10.1371/journal.pbio.3001026

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