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Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain

Signaling between the endoplasmic reticulum (ER) and mitochondria regulates a number of key neuronal functions, many of which are perturbed in Alzheimer's disease. Moreover, damage to ER-mitochondria signaling is seen in cell and transgenic models of Alzheimer's disease. However, as yet th...

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Detalles Bibliográficos
Autores principales: Lau, Dawn H.W., Paillusson, Sebastien, Hartopp, Naomi, Rupawala, Huzefa, Mórotz, Gábor M., Gomez-Suaga, Patricia, Greig, Jenny, Troakes, Claire, Noble, Wendy, Miller, Christopher C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794060/
https://www.ncbi.nlm.nih.gov/pubmed/32682953
http://dx.doi.org/10.1016/j.nbd.2020.105020