Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation

Active telomerase is essential for stem cells and most cancers to maintain telomeres. The enzymatic activity of telomerase is related but not equivalent to the expression of TERT, the catalytic subunit of the complex. Here we show that telomerase enzymatic activity can be robustly estimated from the...

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Detalles Bibliográficos
Autores principales: Noureen, Nighat, Wu, Shaofang, Lv, Yingli, Yang, Juechen, Alfred Yung, W. K., Gelfond, Jonathan, Wang, Xiaojing, Koul, Dimpy, Ludlow, Andrew, Zheng, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794223/
https://www.ncbi.nlm.nih.gov/pubmed/33420056
http://dx.doi.org/10.1038/s41467-020-20474-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794223/
https://www.ncbi.nlm.nih.gov/pubmed/33420056
http://dx.doi.org/10.1038/s41467-020-20474-9

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