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Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation
Active telomerase is essential for stem cells and most cancers to maintain telomeres. The enzymatic activity of telomerase is related but not equivalent to the expression of TERT, the catalytic subunit of the complex. Here we show that telomerase enzymatic activity can be robustly estimated from the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794223/ https://www.ncbi.nlm.nih.gov/pubmed/33420056 http://dx.doi.org/10.1038/s41467-020-20474-9 |