Combinatorial targeting of multiple myeloma by complementing T cell engaging antibody fragments

Bispecific T cell engaging antibodies (BiTEs) address tumor associated antigens that are over-expressed on cancer but that can also be found on healthy tissues, causing substantial on-target/off-tumor toxicities. To overcome this hurdle, we recently introduced hemibodies, a pair of complementary ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Geis, Maria, Nowotny, Boris, Bohn, Marc-Dominic, Kouhestani, Dina, Einsele, Hermann, Bumm, Thomas, Stuhler, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794243/
https://www.ncbi.nlm.nih.gov/pubmed/33420283
http://dx.doi.org/10.1038/s42003-020-01558-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794243/
https://www.ncbi.nlm.nih.gov/pubmed/33420283
http://dx.doi.org/10.1038/s42003-020-01558-0

Ejemplares similares