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Respiratory chain components are required for peptidoglycan recognition protein-induced thiol depletion and killing in Bacillus subtilis and Escherichia coli

Mammalian peptidoglycan recognition proteins (PGRPs or PGLYRPs) kill bacteria through induction of synergistic oxidative, thiol, and metal stress. Tn-seq screening of Bacillus subtilis transposon insertion library revealed that mutants in the shikimate pathway of chorismate synthesis had high surviv...

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Detalles Bibliográficos
Autores principales: Yang, Chun-Kai, Kashyap, Des R., Kowalczyk, Dominik A., Rudner, David Z., Wang, Xindan, Gupta, Dipika, Dziarski, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794252/
https://www.ncbi.nlm.nih.gov/pubmed/33420211
http://dx.doi.org/10.1038/s41598-020-79811-z