Panton-Valentine Leucocidin of Staphylococcus aureus Induces Oxidative Stress and Neurotransmitter Imbalance in a Retinal Explant Model

PURPOSE: Endophthalmitis models have reported the virulent role of Panton-Valentine leucocidin (PVL) secreted by Staphylococcus aureus on the retina. PVL targets retinal ganglion cells (RGCs), expressing PVL membrane receptor C5aR. Interactions between PVL and retinal cells lead to glial activation,...

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Detalles Bibliográficos
Autores principales: Wurtz, Mathieu, Ruhland, Elisa, Liu, XuanLi, Namer, Izzie-Jacques, Mazzoleni, Viola, Lipsker, Dan, Keller, Daniel, Prévost, Gilles, Gaucher, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794257/
https://www.ncbi.nlm.nih.gov/pubmed/33393970
http://dx.doi.org/10.1167/iovs.62.1.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794257/
https://www.ncbi.nlm.nih.gov/pubmed/33393970
http://dx.doi.org/10.1167/iovs.62.1.4

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