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The negative elongation factor NELF promotes induced transcriptional response of Drosophila ecdysone-dependent genes

For many years it was believed that promoter-proximal RNA-polymerase II (Pol II) pausing manages the transcription of genes in Drosophila development by controlling spatiotemporal properties of their activation and repression. But the exact proteins that cooperate to stall Pol II in promoter-proxima...

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Detalles Bibliográficos
Autores principales: Mazina, Marina Yu., Kovalenko, Elena V., Vorobyeva, Nadezhda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794308/
https://www.ncbi.nlm.nih.gov/pubmed/33420323
http://dx.doi.org/10.1038/s41598-020-80650-1