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An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

Prenatal alcohol exposure (PAE) causes permanent cognitive disability. The enteric microbiome generates microbial-dependent products (MDPs) that may contribute to disorders including autism, depression, and anxiety; it is unknown whether similar alterations occur in PAE. Using a mouse PAE model, we...

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Detalles Bibliográficos
Autores principales: Virdee, Manjot S., Saini, Nipun, Kay, Colin D., Neilson, Andrew P., Kwan, Sze Ting Cecilia, Helfrich, Kaylee K., Mooney, Sandra M., Smith, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794323/
https://www.ncbi.nlm.nih.gov/pubmed/33420159
http://dx.doi.org/10.1038/s41598-020-80093-8