YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

Ewing sarcoma (EwS) is a highly metastatic bone cancer characterized by the ETS fusion oncoprotein EWS-FLI1. EwS cells are phenotypically highly plastic and switch between functionally distinct cell states dependent on EWS-FLI1 fluctuations. Whereas EWS-FLI1(high) cells proliferate, EWS-FLI1(low) ce...

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Detalles Bibliográficos
Autores principales: Bierbaumer, Lisa, Katschnig, Anna M., Radic-Sarikas, Branka, Kauer, Maximilian O., Petro, Jeffrey A., Högler, Sandra, Gurnhofer, Elisabeth, Pedot, Gloria, Schäfer, Beat W., Schwentner, Raphaela, Mühlbacher, Karin, Kromp, Florian, Aryee, Dave N. T., Kenner, Lukas, Uren, Aykut, Kovar, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794350/
https://www.ncbi.nlm.nih.gov/pubmed/33419969
http://dx.doi.org/10.1038/s41389-020-00294-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794350/
https://www.ncbi.nlm.nih.gov/pubmed/33419969
http://dx.doi.org/10.1038/s41389-020-00294-8

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