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Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
Expansions of CAG/CTG trinucleotide repeats in DNA are the cause of at least 17 degenerative human disorders, including Huntington’s Disease. Repeat instability is thought to occur via the formation of intrastrand hairpins during replication, repair, recombination, and transcription though relativel...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794359/ https://www.ncbi.nlm.nih.gov/pubmed/33420051 http://dx.doi.org/10.1038/s41467-020-20426-3 |