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Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats

Expansions of CAG/CTG trinucleotide repeats in DNA are the cause of at least 17 degenerative human disorders, including Huntington’s Disease. Repeat instability is thought to occur via the formation of intrastrand hairpins during replication, repair, recombination, and transcription though relativel...

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Detalles Bibliográficos
Autores principales:	Hu, Tianyu, Morten, Michael J., Magennis, Steven W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794359/ https://www.ncbi.nlm.nih.gov/pubmed/33420051 http://dx.doi.org/10.1038/s41467-020-20426-3

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