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EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma

Glioblastoma (GBM) is the most common type of adult malignant brain tumor, but its molecular mechanisms are not well understood. In addition, the knowledge of the disease-associated expression and function of YTHDF2 remains very limited. Here, we show that YTHDF2 overexpression clinically correlates...

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Detalles Bibliográficos
Autores principales: Fang, Runping, Chen, Xin, Zhang, Sicong, Shi, Hui, Ye, Youqiong, Shi, Hailing, Zou, Zhongyu, Li, Peng, Guo, Qing, Ma, Li, He, Chuan, Huang, Suyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794382/
https://www.ncbi.nlm.nih.gov/pubmed/33420027
http://dx.doi.org/10.1038/s41467-020-20379-7