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Bridgin connects the outer kinetochore to centromeric chromatin

The microtubule-binding outer kinetochore is coupled to centromeric chromatin through CENP-C(Mif2), CENP-T(Cnn1), and CENP-U(Ame1) linker pathways originating from the constitutive centromere associated network (CCAN) of the inner kinetochore. Here, we demonstrate the recurrent loss of most CCAN com...

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Detalles Bibliográficos
Autores principales: Sridhar, Shreyas, Hori, Tetsuya, Nakagawa, Reiko, Fukagawa, Tatsuo, Sanyal, Kaustuv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794384/
https://www.ncbi.nlm.nih.gov/pubmed/33420015
http://dx.doi.org/10.1038/s41467-020-20161-9