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PDGFRα mediated survival of myofibroblasts inhibit satellite cell proliferation during aberrant regeneration of lacerated skeletal muscle

Aberrant regeneration or fibrosis in muscle is the denouement of deregulated cellular and molecular events that alter original tissue architecture due to accumulation of excessive extracellular matrix. The severity of the insult to the skeletal muscle determines the nature of regeneration. Numerous...

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Detalles Bibliográficos
Autores principales: Thooyamani, Abinaya Sundari, Mukhopadhyay, Asok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794387/
https://www.ncbi.nlm.nih.gov/pubmed/33420132
http://dx.doi.org/10.1038/s41598-020-79771-4