Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is an aggressive pediatric malignancy of the muscle, that includes Fusion Positive (FP)-RMS harboring PAX3/7-FOXO1 and Fusion Negative (FN)-RMS commonly with RAS pathway mutations. RMS express myogenic master transcription factors MYOD and MYOG yet are unable to terminally dif...

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Detalles Bibliográficos
Autores principales: Pomella, Silvia, Sreenivas, Prethish, Gryder, Berkley E., Wang, Long, Milewski, David, Cassandri, Matteo, Baxi, Kunal, Hensch, Nicole R., Carcarino, Elena, Song, Young, Chou, Hsien-Chao, Yohe, Marielle E., Stanton, Benjamin Z., Amadio, Bruno, Caruana, Ignazio, De Stefanis, Cristiano, De Vito, Rita, Locatelli, Franco, Chen, Yidong, Chen, Eleanor Y., Houghton, Peter, Khan, Javed, Rota, Rossella, Ignatius, Myron S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794422/
https://www.ncbi.nlm.nih.gov/pubmed/33420019
http://dx.doi.org/10.1038/s41467-020-20386-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794422/
https://www.ncbi.nlm.nih.gov/pubmed/33420019
http://dx.doi.org/10.1038/s41467-020-20386-8

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