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Exploring the effect of network topology, mRNA and protein dynamics on gene regulatory network stability

Homeostasis of protein concentrations in cells is crucial for their proper functioning, requiring steady-state concentrations to be stable to fluctuations. Since gene expression is regulated by proteins such as transcription factors (TFs), the full set of proteins within the cell constitutes a large...

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Detalles Bibliográficos
Autores principales: Guo, Yipei, Amir, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794440/
https://www.ncbi.nlm.nih.gov/pubmed/33420076
http://dx.doi.org/10.1038/s41467-020-20472-x