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Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells

Glypican-3 (GPC3) is a cell surface heparan sulfate proteoglycan that is being evaluated as an emerging therapeutic target in hepatocellular carcinoma (HCC). GPC3 has been shown to interact with several extracellular signaling molecules, including Wnt, HGF, and Hedgehog. Here, we reported a cell sur...

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Detalles Bibliográficos
Autores principales: Meng, Panpan, Zhang, Yi-Fan, Zhang, Wangli, Chen, Xin, Xu, Tong, Hu, Sheng, Liang, Xinjun, Feng, Mingqian, Yang, Xiaoqing, Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794441/
https://www.ncbi.nlm.nih.gov/pubmed/33420124
http://dx.doi.org/10.1038/s41598-020-79524-3