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High-resolution single-cell 3D-models of chromatin ensembles during Drosophila embryogenesis
Single-cell chromatin studies provide insights into how chromatin structure relates to functions of individual cells. However, balancing high-resolution and genome wide-coverage remains challenging. We describe a computational method for the reconstruction of large 3D-ensembles of single-cell (sc) c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794469/ https://www.ncbi.nlm.nih.gov/pubmed/33420075 http://dx.doi.org/10.1038/s41467-020-20490-9 |