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RETRACTED ARTICLE: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function

Overcoming tumor-mediated immunosuppression and enhancing cytotoxic T-cell activity within the tumor microenvironment are two central goals of immuno-oncology (IO) drug discovery initiatives. However, exploratory assays involving immune components are often plagued by low-throughput and poor clinica...

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Detalles Bibliográficos
Autores principales: To, Jeremy, Quackenbush, Doug, Rowell, Emily, Li, Lilin, Reed, Connor, Lo, Frederick, Horman, Shane R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794535/
https://www.ncbi.nlm.nih.gov/pubmed/33420321
http://dx.doi.org/10.1038/s42003-020-01565-1