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The severity of the pathogen-induced acute sickness response is affected by polymorphisms in genes of the NLRP3 inflammasome pathway

The acute sickness response (ASR) is a stereotyped set of symptoms including fatigue, pain, and disturbed mood, which are present in most acute infections. The immunological mechanisms of the ASR are conserved, with variations in severity determined partly by the pathogen, but also by polymorphisms...

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Detalles Bibliográficos
Autores principales: Valencia, Braulio M., Cvejic, Erin, Vollmer-Conna, Ute, Hickie, Ian B., Wakefield, Denis, Li, Hui, Pedergnana, Vincent, Rodrigo, Chaturaka, Lloyd, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794598/
https://www.ncbi.nlm.nih.gov/pubmed/33434563
http://dx.doi.org/10.1016/j.bbi.2021.01.005