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Anti-HCMV activity by an irreversible p97 inhibitor LC-1310
The AAA+ (ATPase associated with various cellular activities) protein p97, also called valosin-containing protein, is a hexameric ring ATPase and uses ATP hydrolysis to unfold or extract proteins from biological complexes. Many cellular processes are affected by p97 including ER-associated degradati...
Autores principales: | Wang, Yan, Soto-Acosta, Ruben, Ding, Rui, Chen, Liqiang, Geraghty, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794631/ https://www.ncbi.nlm.nih.gov/pubmed/33456290 http://dx.doi.org/10.1007/s00044-020-02679-1 |
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