Molecular Simulation and Statistical Learning Methods toward Predicting Drug–Polymer Amorphous Solid Dispersion Miscibility, Stability, and Formulation Design

Amorphous solid dispersions (ASDs) have emerged as widespread formulations for drug delivery of poorly soluble active pharmaceutical ingredients (APIs). Predicting the API solubility with various carriers in the API–carrier mixture and the principal API–carrier non-bonding interactions are critical...

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Detalles Bibliográficos
Autores principales: Walden, Daniel M., Bundey, Yogesh, Jagarapu, Aditya, Antontsev, Victor, Chakravarty, Kaushik, Varshney, Jyotika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794704/
https://www.ncbi.nlm.nih.gov/pubmed/33401494
http://dx.doi.org/10.3390/molecules26010182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794704/
https://www.ncbi.nlm.nih.gov/pubmed/33401494
http://dx.doi.org/10.3390/molecules26010182

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