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Metformin Preserves β-Cell Compensation in Insulin Secretion and Mass Expansion in Prediabetic Nile Rats

Prediabetes is a high-risk condition for type 2 diabetes (T2D). Pancreatic β-cells adapt to impaired glucose regulation in prediabetes by increasing insulin secretion and β-cell mass expansion. In people with prediabetes, metformin has been shown to prevent prediabetes conversion to diabetes. Howeve...

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Detalles Bibliográficos
Autores principales: Huang, Hui, Lorenz, Bradi R., Zelmanovitz, Paula Horn, Chan, Catherine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794750/
https://www.ncbi.nlm.nih.gov/pubmed/33401592
http://dx.doi.org/10.3390/ijms22010421