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Metformin Preserves β-Cell Compensation in Insulin Secretion and Mass Expansion in Prediabetic Nile Rats
Prediabetes is a high-risk condition for type 2 diabetes (T2D). Pancreatic β-cells adapt to impaired glucose regulation in prediabetes by increasing insulin secretion and β-cell mass expansion. In people with prediabetes, metformin has been shown to prevent prediabetes conversion to diabetes. Howeve...
Autores principales: | Huang, Hui, Lorenz, Bradi R., Zelmanovitz, Paula Horn, Chan, Catherine B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794750/ https://www.ncbi.nlm.nih.gov/pubmed/33401592 http://dx.doi.org/10.3390/ijms22010421 |
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