Nicotine Changes Airway Epithelial Phenotype and May Increase the SARS-COV-2 Infection Severity

(1) Background: Nicotine is implicated in the SARS-COV-2 infection through activation of the α7-nAChR and over-expression of ACE2. Our objective was to clarify the role of nicotine in SARS-CoV-2 infection exploring its molecular and cellular activity. (2) Methods: HBEpC or si-mRNA-α7-HBEpC were trea...

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Detalles Bibliográficos
Autores principales: Lupacchini, Leonardo, Maggi, Fabrizio, Tomino, Carlo, De Dominicis, Chiara, Mollinari, Cristiana, Fini, Massimo, Bonassi, Stefano, Merlo, Daniela, Russo, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794754/
https://www.ncbi.nlm.nih.gov/pubmed/33379366
http://dx.doi.org/10.3390/molecules26010101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794754/
https://www.ncbi.nlm.nih.gov/pubmed/33379366
http://dx.doi.org/10.3390/molecules26010101

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