Evaluation of the Physicochemical Properties, Pharmacokinetics, and In Vitro Anticancer Effects of Docetaxel and Osthol Encapsulated in Methoxy Poly(ethylene glycol)-b-Poly(caprolactone) Polymeric Micelles

Docetaxel (DTX), a taxane-based anticancer drug, and osthol (OTH), a coumarin-derivative compound, have shown anticancer effects against different types of cancers through various mechanisms. However, these drugs have low solubility in water and low oral bioavailability, and thus their clinical appl...

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Detalles Bibliográficos
Autores principales: Jo, Min Jeong, Lee, Yu Jin, Park, Chun-Woong, Chung, Youn Bok, Kim, Jin-Seok, Lee, Mi Kyeong, Shin, Dae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794789/
https://www.ncbi.nlm.nih.gov/pubmed/33379376
http://dx.doi.org/10.3390/ijms22010231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794789/
https://www.ncbi.nlm.nih.gov/pubmed/33379376
http://dx.doi.org/10.3390/ijms22010231

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