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Evaluation of the Physicochemical Properties, Pharmacokinetics, and In Vitro Anticancer Effects of Docetaxel and Osthol Encapsulated in Methoxy Poly(ethylene glycol)-b-Poly(caprolactone) Polymeric Micelles
Docetaxel (DTX), a taxane-based anticancer drug, and osthol (OTH), a coumarin-derivative compound, have shown anticancer effects against different types of cancers through various mechanisms. However, these drugs have low solubility in water and low oral bioavailability, and thus their clinical appl...
Autores principales: | Jo, Min Jeong, Lee, Yu Jin, Park, Chun-Woong, Chung, Youn Bok, Kim, Jin-Seok, Lee, Mi Kyeong, Shin, Dae Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794789/ https://www.ncbi.nlm.nih.gov/pubmed/33379376 http://dx.doi.org/10.3390/ijms22010231 |
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