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Flavonoids Targeting HIF-1: Implications on Cancer Metabolism

SIMPLE SUMMARY: This comprehensive review discusses the anticancer effects of plant phenolic compounds, known as flavonoids, through the targeting of HIF-1 and critical enzymes contributing to the Warburg effect. Connections between HIF-1 and metabolic reprogramming seem to play a crucial role in ca...

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Detalles Bibliográficos
Autores principales: Samec, Marek, Liskova, Alena, Koklesova, Lenka, Mersakova, Sandra, Strnadel, Jan, Kajo, Karol, Pec, Martin, Zhai, Kevin, Smejkal, Karel, Mirzaei, Sepideh, Hushmandi, Kiavash, Ashrafizadeh, Milad, Saso, Luciano, Brockmueller, Aranka, Shakibaei, Mehdi, Büsselberg, Dietrich, Kubatka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794792/
https://www.ncbi.nlm.nih.gov/pubmed/33401572
http://dx.doi.org/10.3390/cancers13010130