Cargando…

Therapeutic Potential of the Molecular Chaperone and Matrix Metalloproteinase Inhibitor Clusterin for Dry Eye

Evidence is presented herein supporting the potential of the natural homeostatic glycoprotein CLU (clusterin) as a novel therapeutic for the treatment of dry eye. This idea began with the demonstration that matrix metalloproteinase MMP9 is required for damage to the ocular surface in mouse dry eye....

Descripción completa

Detalles Bibliográficos
Autores principales: Fini, M. Elizabeth, Jeong, Shinwu, Wilson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7794831/
https://www.ncbi.nlm.nih.gov/pubmed/33374364
http://dx.doi.org/10.3390/ijms22010116